- PII
- 10.31857/S0132344X24010035-1
- DOI
- 10.31857/S0132344X24010035
- Publication type
- Article
- Status
- Published
- Authors
- Volume/ Edition
- Volume 50 / Issue number 1
- Pages
- 19-25
- Abstract
- Biocompatible metal-organic framework MIL-100(Fe) was used as a container for a model hydrophobic active pharmaceutical ingredient, ibuprofen, in composite films based on gelatin, pectin, and kappacarrageenan. According to powder X-ray diffraction and scanning electron microscopy data, the metal-organic framework retained the crystal structure and its particles were uniformly distributed throughout the hydrocolloid matrix. Testing of the obtained film materials under simulated biological conditions using chromatography – mass spectrometry analysis showed that they are applicable as a dosage form for slow release of active pharmaceutical ingredients.
- Keywords
- адресная доставка активные фармацевтические субстанции биосовместимые материалы гидроколлоиды металлорганические координационные полимеры пленки
- Date of publication
- 15.01.2024
- Year of publication
- 2024
- Number of purchasers
- 0
- Views
- 34
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