RAS Chemistry & Material ScienceКоординационная химия Russian Journal of Coordination Chemistry

  • ISSN (Print) 0132-344X
  • ISSN (Online) 3034-5499

New cobalt complex with dihydroxycoumarin: synthesis and kinetics of its redox-activated dissociation

PII
10.31857/S0132344X24030059-1
DOI
10.31857/S0132344X24030059
Publication type
Article
Status
Published
Authors
Volume/ Edition
Volume 50 / Issue number 3
Pages
200-208
Abstract
A new redox-active cobalt(III) complex containing the 2-oxo-2Н-chromene-6,7-diolate dianion and 4,4ʹ-dimethoxy-2,2ʹ-bipyridine as ligands is synthesized. The reduction of the sythesized complex with ascorbic acid in an inert atmosphere is studied in situ by NMR spectrocopy. The reduction is shown to result in the release of 6,7-dihydrocycoumarin acting as a model drug. This process has the first order with respect to the initial complex.
Keywords
in situ спектроскопия ядерного магнитного резонанса дигидроксикумарин комплексы кобальта редокс-активируемая доставка лекарственных препаратов
Date of publication
15.03.2024
Year of publication
2024
Number of purchasers
0
Views
11

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